Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration
K. Wert, G. Velez, K. Vijayalakshmi, V. Shankar, J. Sengillo, R. N. Zare, A. G. Bassuk, S. H. Tsang, V. B. Mahajan
The study identifies proteomic and metabolite pathways affected in retinal neurodegeneration and shows that replenishing TCA cycle metabolites provides neuroprotection.
bioRxiv · Sep 10, 2019Biochemistry