Biophysical characterization of the oligomeric states of recombinant Immunoglobulins type-M and their C1q binding kinetics by Biolayer Interferometry
A. Chouquet, A. J. Pinto, J. Hennicke, W. L. W. Ling, I. Bally, L. Schwaigerlehner, N. M. Thielens, R. Kunert, J.-B. REISER
This study characterizes the oligomeric states and C1q binding kinetics of recombinant IgMs using biophysical methods, showing they retain complement activation function similar to plasma-derived IgMs.
bioRxiv · Sep 30, 2021 · PreprintBioengineering