Engaging the A-Class Antibody: Variable-Heavy (VH) region influencing IgA1 engagement of FcαRI and superantigen proteins G, A, and L.
W.-L. Ling, C. T. Su, W.-H. Lua, J. Y. Yeo, J.-J. Poh, Y.-L. Ng, A. Wipat, S. K. Gan
This study investigates how the variable-heavy (VH) region of IgA1 and A2 influences FcαRI and superantigen protein binding, revealing structural and functional differences between subtypes.
bioRxiv · Sep 27, 2021 · PreprintImmunology