Author

W.-L. Ling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Wipat· 2 shared J. Y. Yeo· 2 shared J.-J. Poh· 2 shared S. K. Gan· 2 shared W.-H. Lua· 2 shared Y.-L. Ng· 2 shared C. T. Su· 1 shared C. T.-T. Su· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. Wipat

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Author profile →

4 papers

Recent·Most cited

The synergistic effects of the VH families and CH regions of multimeric IgM on its interaction with Fc(mu)R, and antigen.

W.-L. Ling, S. K. Gan

The paper investigates how the VH families and CH regions of IgM influence Fc(mu)R and antigen interactions through biolayer interferometry with engineered IgM variants.

bioRxiv · May 19, 2022 · PreprintImmunology

Engaging the A-Class Antibody: Variable-Heavy (VH) region influencing IgA1 engagement of FcαRI and superantigen proteins G, A, and L.

W.-L. Ling, C. T. Su, W.-H. Lua, J. Y. Yeo, J.-J. Poh, Y.-L. Ng, A. Wipat, S. K. Gan

This study investigates how the variable-heavy (VH) region of IgA1 and A2 influences FcαRI and superantigen protein binding, revealing structural and functional differences between subtypes.

bioRxiv · Sep 27, 2021 · PreprintImmunology

Molecular insight into Nickel(II) binding by Her2-specific IgE: a possible mechanistic insight into the pathogenesis of Type I nickel hypersensitivity

C. T.-T. Su, W.-H. Lua, J.-J. Poh, W.-L. Ling, J. Y. Yeo, S. K.-E. Gan

The paper investigates how Her2-specific IgE binds Nickel(II) and suggests this mechanism may explain Type I nickel hypersensitivity and its potential applications in therapeutics and biotechnology.

bioRxiv · Jul 14, 2020 · PreprintImmunology

The Quantification of Antibody Elements and Receptors subunit expression using qPCR: The Design of VH, VL, CH, CL, FcR subunits primers for a more holistic view of the immune system.

W.-L. Ling, Y.-L. Ng, A. Wipat, D. P. Lane, S. Gan

The paper designs qPCR primers to quantify antibody elements and their receptors in PBMC cDNA, enabling a holistic view of immune system gene expression.

bioRxiv · Jul 26, 2019Immunology