Author

Jack Case

Dalhousie University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Denys A. KhaperskyyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

1 paper

Recent·Most cited

Impaired host shutoff is a fitness cost associated with baloxavir marboxil resistance mutations in influenza A virus PA/PA-X nuclease domain.

Jack Case, Denys A. Khaperskyy

This paper shows that baloxavir resistance mutations in the PA protein impair host shutoff activity of PA-X, potentially limiting the spread of resistant influenza viruses.

PLoS Pathogens · Feb 9, 2026Peer-reviewedMicrobiology