Author

Jaclyn Robustelli

Merck & Co., Inc., Rahway, NJ, USA (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein sequence· 1

Frequent Co-Authors

Adam B. Weinglass· 1 shared Aileen Soriano· 1 shared David G. McLaren· 1 shared Elsa Beyer KralliD· 1 shared Gireedhar VenkatachalamiD· 1 shared Haihong ZhouiD· 1 shared Hubert B. JosieniD· 1 shared Huifang YaoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adam B. Weinglass

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1 paper

Recent·Most cited

Discovery of an NRAS isoform and activation-state selective macrocyclic peptide

Kenneth K. Hallenbeck, Yunpeng Zhou, Hubert B. Josien, Songnian Lin, Aileen Soriano, Mayhood Todd, Jaclyn Robustelli, Xiaomei Chai, My Sam Mansueto, Gireedhar Venkatachalam, Ryan E. Loy, Peng‐Hsun Chase Chen, Huifang Yao, Haihong Zhou, Elsa Beyer Krall, , S. Adrian Saldanha

The paper identifies a macrocyclic peptide that selectively binds NRAS with isoform and activation-state specificity, but lacks membrane permeability and functional inhibition.

bioRxiv · Jul 31, 2026 · PreprintCancer Biology