Author

Jacob Pope

University of YorkPrimary ORCID profile (0009-0004-8970-0456 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Jacob PopeiD1 paper · University of York

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew N. HoldingiD· 1 shared Jack StenningiD· 1 shared Jakub Lukaszonek· 1 shared Jodie R. MalcolmiD· 1 shared Katherine S. BridgeiD· 1 shared Lesley Gilbert· 1 shared Sally R. JamesiD· 1 shared Susanna F RoseiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrew N. HoldingORCID

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1 paper

Recent·Most cited

An ERα-Dependent Hypoxia Response Defines EMT-Adjacent Tumour Regions and Suppresses the Pro-survival Effects of Amiloride in Estrogen Receptor-Positive Breast Cancer

Jodie R. Malcolm, Jack Stenning, Jacob Pope, Jakub Lukaszonek, Susanna F Rose, Taylor E. Smith, Lesley Gilbert, Sally R. James, Katherine S. Bridge, William J. Brackenbury, Andrew N. Holding

The paper identifies an ERα-dependent hypoxia response in ER+ breast cancer that influences gene expression and sensitivity to amiloride, linking hypoxia and ER signaling.

bioRxiv · Oct 3, 2025 · PreprintCancer Biology