Author

Jaividhya Dasarathy

MetroHealth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:mouse· 1

Frequent Co-Authors

Annette BellariD· 3 shared David W. StreemiD· 3 shared Nicole WelchiD· 3 shared Srinivasan DasarathyiD· 3 shared Laura E. NagyiD· 2 shared Megan R. McMulleniD· 2 shared Vai PathakiD· 2 shared Adam KimiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

Annette BellarORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Urine proteomic profiling at admission reveals complement biomarkers linked to alcohol-associated liver disease.

Luan Gavião Prado, Ryan J. Musich, Moyinoluwa Taiwo, Vai Pathak, Daniel Miller Rotroff, Annette Bellar, Nicole Welch, Jaividhya Dasarathy, David W. Streem, for the AlcHepNet, Srinivasan Dasarathy, Laura E. Nagy

The paper identifies complement biomarkers in urine linked to alcohol-associated liver disease and provides insights into liver-kidney crosstalk mechanisms.

Alcoholism Clinical and Experimental Research · Jun 1, 2026Peer-reviewedImmunology

Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis

Adam Kim, Megan R. McMullen, Annette Bellar, David W. Streem, Jaividhya Dasarathy, Nicole Welch, Srinivasan Dasarathy

The paper uses Hi-C and scRNA-seq to analyze chromatin structure and gene expression in monocytes from alcohol-associated hepatitis patients, finding altered genome organization affecting immune gene expression.

bioRxiv · Aug 7, 2024 · PreprintImmunology

Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury

Venkateshwari Varadharajan, Iyappan Ramachandiran, William J. Massey, Raghav Jain, Rakhee Banerjee, Anthony J. Horak, Megan R. McMullen, Emily Huang, Annette Bellar, Shuhui Wang Lorkowski, Kailash Gulshan, Robert Nathaniel Helsley, Isabella James, Vai Pathak, Jaividhya Dasarathy, , Jonathan Mark Brown

This study shows that MBOAT7 loss of function in hepatocytes causes ethanol-induced liver injury by disrupting lysosomal biogenesis and autophagic flux.

eLife · Dec 27, 2023Peer-reviewedMolecular Biology