Author

Jake Jensen

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amine Chahin· 1 shared Carla F. KimiD· 1 shared Gowtham Boosarpu· 1 shared Janine Gote-SchnieringiD· 1 shared Jia-qi Wang· 1 shared Kai GuoiD· 1 shared M Königshoff· 1 shared M. Camila Melo-NarváeziD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Amine Chahin

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1 paper

Recent·Most cited

Local IFNγ signaling contributes to the regenerative decline of aged alveolar progenitor cells

Jake Jensen, Kai Guo, Janine Gote-Schniering, Meeta Mistry, Zane Orinska, Jia-qi Wang, M. Camila Melo-Narváez, Gowtham Boosarpu, Amine Chahin, Margherita Paschini, Madison Seymour, Patrizia Pessina, Susanna M. Dang, Qianjiang Hu, Shannan Ho Sui, , Carla F. Kim

This study shows that local IFNγ signaling in aged lungs impairs alveolar progenitor cell regeneration, and reducing IFNγ levels restores regenerative capacity.

bioRxiv · Apr 9, 2026 · PreprintCell Biology