Loss of circulating CD8α+ NK cells during human Mycobacterium tuberculosis infection
Nezar Mehanna, Atul Pradhan, Rimanpreet Kaur, Theodota Kontopoulos, Barbara Rosati, David Carlson, Nai-Kong Cheung, Hong Xu, James Bean, Katherine Hsu, Jean-Benoit Le Luduec, Charles Kyriakos Vorkas
The paper identifies CD8+ NK cells as a Mtb-responsive population with enhanced maturity and cytotoxicity in human TB infection, correlating with disease resistance.
bioRxiv · Apr 16, 2024 · PreprintImmunology