Author

James Bole Pan

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aaron G. SchmidtiD· 1 shared Adam J. RubiniD· 1 shared Alex K. ShalekiD· 1 shared Avanyish Toniappa· 1 shared Constantine N. TzouanasiD· 1 shared Dana T. Lamson· 1 shared Douglas S. KwoniD· 1 shared Ella G. Sobieszczyk· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Aaron G. SchmidtORCID

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1 paper

Recent·Most cited

Decoding & manipulating human intercellular signaling via scalable cell-free protein synthesis

Constantine N. Tzouanas, Feng Shan, Manuel Guzman, Tracy Leidan Chen, James Bole Pan, Adam J. Rubin, Ella G. Sobieszczyk, Keith D. Rivera, Avanyish Toniappa, Dana T. Lamson, Lucía Castelló-Pedrero, Krista L. Dong, Vanessa Pillay, Stuart S. Levine, Steven A. Carr, , Alex K. Shalek

The paper develops scalable cell-free protein synthesis platforms to generate single-cell RNA-sequencing data on immune cell responses to cytokines and other signals, enabling functional discovery and drug target prioritization.

bioRxiv · Oct 26, 2026 · PreprintSystems Biology