Predictive control of human pancreatic cell fate using a digital model of in vitro differentiation
Enrique Eduardo Sanchez-Castro, Matthew Ishahak, Tai Le, Marlie M. Maestas, Diana C. Hernandez-Rincon, Noyonika Mukherjee, Kameron Bradley, James Lu, Sarah E. Gale, Jeffrey R. Millman
The paper develops a predictive digital model of human pancreatic cell differentiation using single-cell multiomic data to identify regulators and validate their roles in islet fate specification.
bioRxiv · Sep 17, 2026 · PreprintCell Biology