Author

James R. Bone

EpiCypher (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CUT&Tag· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Matthew R. MarundeiD· 2 shared Zu‐Wen SuniD· 2 shared Alexander S. LeeiD· 1 shared Allison R. HickmaniD· 1 shared Andrea L. JohnstoneiD· 1 shared Anup VaidyaiD· 1 shared Benjamin M. LortoniD· 1 shared Brandon A. BooneiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

Matthew R. MarundeORCID

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Author profile →

2 papers

Recent·Most cited

Nucleosome context regulates chromatin reader preference

Matthew R. Marunde, Irina K Popova, Nathan W Hall, Anup Vaidya, James R. Bone, Brandon A. Boone, Peter J. Brown, Ryan J. Ezell, Tessa M. Firestone, Harrison A. Fuchs, Elisa Gibson, Zachary B Gillespie, Susan L. Gloor, Allison R. Hickman, Sarah A Howard, , Jonathan M. Burg

The paper investigates how nucleosome context influences chromatin reader binding preferences using biochemical and genomic approaches, revealing that multivalent engagement often has regulatory effects beyond simple additivity.

Nucleic Acids Research · Oct 1, 2025Peer-reviewedBiochemistry

Transcriptomic and proteomic regulation through abundant, dynamic, and independent arginine methylation by Type I and Type II PRMTs

Maxim I. Maron, Stephanie M. Lehman, Sitaram Gayatri, Joseph D. DeAngelo, Subray S. Hegde, Benjamin M. Lorton, Yan Sun, Dina L. Bai, Simone Sidoli, Varun Gupta, Matthew R. Marunde, James R. Bone, Zu‐Wen Sun, Mark T. Bedford, Jeffrey Shabanowitz, , David Shechter

The paper investigates the substrate preferences and functional consequences of Type I and II PRMTs by inhibiting them in A549 cells and analyzing proteomic and transcriptomic changes.

iScience · Aug 11, 2021Peer-reviewedMolecular Biology