Jeffrey Shabanowitz

The paper shows CDK8 phosphorylates DELLA to limit Mediator recruitment, affecting GA signaling in Arabidopsis.

This study shows that SPINDLY-mediated O-fucosylation of ARF6 and ARF8 inhibits their interaction with the coactivator Mediator complex, reducing fruit growth in Arabidopsis.

This study identifies TTLL4 as a therapeutic target in NPM1-mutated AML by showing its role in stabilizing NPM1c and promoting differentiation block, with a small molecule inhibitor demonstrating efficacy.

This paper characterizes protamines in the noble false widow spider Steatoda nobilis, revealing liquid-liquid phase separation during spermiogenesis and evolutionary links to histone H1.

This study identifies phosphorylation as a new regulatory mechanism for DELLA activity by enhancing its binding to histone H2A at target chromatin in Arabidopsis.

The paper shows that glutamylation of acidic IDRs in Npm2 and Nap1 enhances their DNA mimicry function, improving histone chaperone efficiency in nucleosome assembly.

The paper investigates the substrate preferences and functional consequences of Type I and II PRMTs by inhibiting them in A549 cells and analyzing proteomic and transcriptomic changes.