Caveolin assemblies displace one bilayer leaflet to organize and bend membranes
Milka Doktorova, Sebastian Daum, Tyler R. Reagle, Hannah I. Cannon, Jan Ebenhan, Sarah Neudorf, Bing Han, Satyan Sharma, Peter M. Kasson, Kandice R. Levental, Kirsten Bacia, Anne K. Kenworthy, Ilya Levental
This paper investigates how the CAV1-8S caveolin complex interacts with lipid membranes through a novel leaflet replacement mechanism, revealing its role in membrane curvature and organization.
Proceedings of the National Academy of Sciences · May 13, 2025Peer-reviewedBiophysics