Regulatory mechanisms are revealed by the distribution of transcription initiation times in single microbial cells
Sandeep Choubey, Jane Kondev, Alvaro Sanchez
bioRxiv · Nov 22, 2017 · PreprintBiophysics
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4 papers
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Sandeep Choubey, Jane Kondev, Alvaro Sanchez
bioRxiv · Nov 22, 2017 · PreprintBiophysics
Lishibanya Mohapatra, Thibaut J. Lagny, David Harbage, Predrag R. Jelenkovic, Jane Kondev
This paper shows the limiting-pool mechanism cannot control lengths of multiple filamentous structures sharing a common subunit pool, leading to size fluctuations and one dominant structure.
bioRxiv · Sep 16, 2016 · PreprintBiophysics
The paper models the size regulation of multi-filament structures assembled from a shared finite subunit pool and finds that individual filaments have a power-law length distribution.
bioRxiv · May 3, 2016Biophysics
Joseph Rauch, Jane Kondev, Alvaro Sanchez
The paper shows that improving evolutionary stability of public goods cooperators in microbial populations reduces their ecological stability, and complex regulatory strategies can overcome this tradeoff.
bioRxiv · Feb 15, 2016 · PreprintEvolutionary Biology