Author

Jason A. Garness

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin Garrett VincentiD· 3 shared Jessica Alley· 2 shared Mitra ShabrangiD· 2 shared Alex M. JaegeriD· 1 shared Alex RubinsteyniD· 1 shared Ali Younas KhaniD· 1 shared Amber Smith· 1 shared Brandon W. Carpenter· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

Benjamin Garrett VincentORCID

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Author profile →

3 papers

Recent·Most cited

Discovery of frameshift-associated TCRs following personalized neoantigen vaccination in a patient with osteosarcoma

Sarah Bennett, Jessica Alley, Mitra Shabrang, Jason A. Garness, Karen McKinnon, Amber Smith, William Blake Inabinett, William Arthur Hoos, Marshall A. Thompson, Alex Rubinsteyn, Benjamin Garrett Vincent

The paper reports the discovery of TCRs specific to vaccine peptides in a patient with osteosarcoma following personalized neoantigen vaccination and in vitro expansion.

bioRxiv · Oct 15, 2026 · PreprintImmunology

Immunodominance Hierarchy of Endogenous BBN963 Bladder Cancer Antigens Remains Stable Under Anti-PD1 and Anti-CTLA4 Immunotherapy

Misha Fini, Jessica Alley, Steven P. Vensko II, Dhuvarakesh Karthikeyan, Jin Seok Lee, Jason A. Garness, Emily Paul, Alex M. Jaeger, Nilu P Goonetilleke, William Y. Kim, Benjamin Garrett Vincent

This study identifies a stable immunodominance hierarchy of tumor antigens in a murine bladder cancer model under anti-PD1 and anti-CTLA4 therapy, suggesting broad antigen selection could improve immunotherapy.

bioRxiv · May 27, 2026 · PreprintCancer Biology

Alcohol use reduces the efficacy of anti-PD1 immunotherapy by disrupting anti-tumor immunity

Kristen N. Gilley, Jason A. Garness, Ali Younas Khan, Brandon W. Carpenter, Mitra Shabrang, Wolfgang Beckabir, Chad Victor Pecot, Benjamin Garrett Vincent, Leon G. Coleman

This study shows alcohol use reduces anti-PD1 immunotherapy efficacy in cancer patients and mouse models by impairing T cell function and anti-tumor immunity.

bioRxiv · Jul 14, 2025 · PreprintImmunology