Author

Jay Hirsh

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Karol CichewicziD· 3 shared Amy HuiD· 1 shared Andrew L. LemireiD· 1 shared Ashok Litwin-KumariD· 1 shared Brandi SharpiD· 1 shared Christina P. Christoforou· 1 shared Daniel BusheyiD· 1 shared Gerald M. RubiniD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Karol CichewiczORCID

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3 papers

Recent·Most cited

Non-uniform chromosomal SNP density biases sites of meiotic crossovers in Drosophila melanogaster

Savanna Hinson, Ryan Sangston, Karol Cichewicz, Guruprasad Varma Konduru, Ishan Parikh, Jay Hirsh

The paper identifies how uneven SNP distribution on the X-chromosome of Drosophila affects meiotic crossover sites, reducing mapping resolution for genetic traits.

G3 Genes Genomes Genetics · Apr 15, 2026Peer-reviewedGenetics

Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics

Yoshinori Aso, Robert P. Ray, Xi Long, Daniel Bushey, Karol Cichewicz, Teri-T B. Ngo, Brandi Sharp, Christina P. Christoforou, Amy Hu, Andrew L. Lemire, Paul W. Tillberg, Jay Hirsh, Ashok Litwin-Kumar, Gerald M. Rubin

The paper shows nitric oxide acts as a cotransmitter in dopaminergic neurons to modulate memory dynamics in Drosophila.

eLife · Nov 14, 2019Peer-reviewedNeuroscience

Transcriptome responses to reduced dopamine in the Substantia Nigra Pars Compacta reveals a potential protective role for dopamine.

M. Koltun, Karol Cichewicz, Jeffrey T. Gibbs, Martin Darvas, Jay Hirsh

The paper uses a genetic model to study transcriptome changes in dopamine-depleted mice, finding DA-dependent gene expression in SNc that suggests a protective role for dopamine.

bioRxiv · Sep 9, 2019 · PreprintNeuroscience