The quest continues: Human CD4+ CD16+ CD56+ "exTreg" resemble NKT cells instead
Jeevan Mutha, Meghana Konga, Maximilian Sprang, Johannes U. Mayer, Susan Schlenner
The paper re-evaluates the identity of CD4+ CD56+ CD16+ cells in human PBMC, finding they resemble NKT cells rather than exTreg, and explores Treg stability and Tr17 induction for therapeutic applications.
bioRxiv · Aug 5, 2025 · PreprintImmunology