Author

Jeffrey Chicca

Primary ORCID profile (0009-0009-5153-5914 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Jeffrey ChiccaiD1 paper · University of Massachusetts Chan Medical School

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Arvind Rao· 1 shared Chong Zhao· 1 shared Evan FarkashiD· 1 shared Evan KelleriD· 1 shared Jeffrey L. PlattiD· 1 shared Joshua HaniD· 1 shared Lev AxenoviD· 1 shared Lwar NaingiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Arvind Rao

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1 paper

Recent·Most cited

Complement C3d enables protective immunity capable of distinguishing spontaneously transformed from non-transformed cells

Jeffrey L. Platt, Chong Zhao, Jeffrey Chicca, Matthew J. Pianko, Joshua Han, Stephanie The, Arvind Rao, Evan Keller, Mayara Garcia de Mattos Barbosa, Lwar Naing, Tracy Pasieka-Axenov, Lev Axenov, Simon Schaefer, Evan Farkash, Marilia Cascalho

This study shows that intracellular C3d enhances immune surveillance by inducing T cell responses against malignant plasma cells while sparing normal cells in a murine model of multiple myeloma.

bioRxiv · Jul 31, 2024 · PreprintImmunology