Jennifer Grubb

Chk2 homologue Mek1 limits Exo1-dependent DNA end resection during meiotic recombination in S. cerevisiae

The paper shows that Mek1, a meiotic kinase, limits Exo1-dependent DNA end resection during meiotic recombination in yeast, using a different mechanism than Rad53 in mitosis.

A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability

The paper identifies a Dmc1 mutant that bypasses Mei5-Sae3, revealing independent roles of Mei5-Sae3 and Rad51 in Dmc1 filament stability and recombination accuracy.

The ATPase activity of E. coli RecA prevents accumulation of toxic complexes formed by erroneous binding to undamaged double strand DNA

The paper shows that RecA's ATPase activity prevents toxic DNA-bound complexes formed by erroneous binding to undamaged dsDNA in E. coli.