Differential modulation of thermal preference after sensitization by optogenetic or pharmacological activation of heat-sensitive nociceptors
Jerry Li, Maham Zain, Robert P. Bonin
This paper develops a behavioral assay to measure thermal preference in mice after peripheral sensitization, showing that capsaicin induces cold preference and gabapentin reverses it, while optogenetic activation of central terminals does not.
Molecular Pain · Jan 1, 2021Peer-reviewedNeuroscience