Author

Jesus Garcia-Lerena

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Eran R. AndrechekiD· 3 shared John VusichiD· 2 shared Morgan Atkins· 2 shared Mylena M.O. Ortiz· 2 shared Aishwarya V. BhurkeiD· 1 shared Andrew C. NelsoniD· 1 shared Anthony Schulte· 1 shared Bin CheniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Eran R. AndrechekORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Tumor-derived FXII engages the intrinsic coagulation cascade to support breast cancer liver metastasis.

Jesus Garcia-Lerena, Jing-Ru Jhan, Nabasmita Talukdar, John Vusich, Mylena M.O. Ortiz, Anthony Schulte, Morgan Atkins, Deeya Patel, Daniel P. Hollern, Monika Quackenbush, Briana To, Sarah Marei, Hui WangL, Y. Lu, Theresa Kiki-Teboum, , Eran R. Andrechek

This study identifies tumor-derived FXII as a driver of liver metastasis in breast cancer by engaging the intrinsic coagulation cascade, with anti-coagulation reducing metastasis in a mouse model.

bioRxiv · Jun 8, 2026 · PreprintCancer Biology

Mammary Alveolar Proliferation and Differentiation During Early Pregnancy is Regulated by E2F5

John Vusich, Jesus Garcia-Lerena, Ryan Corfixsen, Rawan Talib, Morgan Atkins, Aishwarya V. Bhurke, Ripla Arora, Eran R. Andrechek

This study shows E2F5 promotes differentiation of luminal progenitors into alveolar precursors during early pregnancy, coordinating proliferation and differentiation in mammary development.

bioRxiv · Nov 27, 2024 · PreprintDevelopmental Biology

Unraveling the role of receptor-like protein tyrosine phosphatase PTPRH in cell signaling regulation and biological processes of non-small cell lung cancer

Mylena M.O. Ortiz, Dhanvin Hetarth Patel, Jesus Garcia-Lerena, Andrew C. Nelson, Matthew Swiatnicki, Eran R. Andrechek

This study identifies PTPRH's role in NSCLC by revealing its interactions and signaling effects, showing it suppresses tumor growth and migration.

bioRxiv · Jun 13, 2024 · PreprintCancer Biology