Author

Jiahui Yan

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

Chuan-Wei Chen· 2 shared Dehua YangiD· 2 shared Fenghui Zhao· 2 shared H. Eric XuiD· 2 shared Ming‐Wei WangiD· 2 shared Qingtong ZhouiD· 2 shared Antao DaiiD· 1 shared Anyi Liang· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Chuan-Wei Chen

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2 papers

Recent·Most cited

A unique peptide recognition mechanism by the human relaxin family peptide receptor 4 (RXFP4)

Yan Chen, Qingtong Zhou, Jiang Wang, Youwei Xu, Yun Wang, Jiahui Yan, Yibing Wang, Qi Zhu, Fenghui Zhao, Chenghao Li, Chuan-Wei Chen, Xiaoqing Cai, Ross A. D. Bathgate, Chun Shen, H. Eric Xu, , Ming‐Wei Wang

The paper reports cryo-EM structures of RXFP4-Gi complexes with INSL5 and agonists, revealing a unique peptide-binding mechanism and subtype selectivity determinants.

bioRxiv · Jul 28, 2022 · PreprintMolecular Biology

A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2

Yingna Xu, Wenbo Feng, Qingtong Zhou, Anyi Liang, Jie Li, Antao Dai, Fenghui Zhao, Jiahui Yan, Chuan-Wei Chen, Hao Li, Lihua Zhao, Tian Xia, Yan Zhang, H. Eric Xu, Dehua Yang, Ming‐Wei Wang

This study reports the cryo-EM structure of the human VIP2R bound to PACAP27 and Gs, revealing a unique N-terminal helix conformation that stabilizes the ligand-receptor interface.

Nature Communications · Apr 27, 2022Peer-reviewedMolecular Biology