Author

Jiaming Weng

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:variant calling· 2

Frequent Co-Authors

Joseph G. GleesoniD· 3 shared Changuk ChungiD· 2 shared Chelsea BarrowsiD· 2 shared Naomi Meave Ojeda· 2 shared Robyn Ann HowarthiD· 2 shared Stephen Francis KingsmoreiD· 2 shared Xiaoxu YangiD· 2 shared Arzoo PateliD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Joseph G. GleesonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Benchmarked sequencing methods reveal hidden mosaic variation in the human brain

Jiaming Weng, Do Hyeon Cha, Jinhui Chun, Pablo Santamarina‐Ojeda, Yuhe Cheng, Robyn Howarth, Yixuan Xu, Xiangyu Huangfu, Pei-Jhen Wang, Saehoon Jung, Jinhee Ryu, Yunhye Noh, Sangmoon Lee, Xiaoxu Yang, Young Seok Ju, , Joseph G. Gleeson

The paper benchmarks sequencing methods to recover mosaic variants in human brain tissue and introduces RIVER to enhance variant detection across methods.

bioRxiv · Oct 13, 2026 · PreprintGenomics

Genomic mosaicism reveals developmental organization of trunk neural crest-derived ganglia

Keng Ioi Vong, Yanina D. Álvarez, Qingquan Zhang, Jiaming Weng, Geoffroy P. J. C. Noël, Scott T. Barton, Changuk Chung, Robyn Ann Howarth, Naomi Meave Ojeda, Fiza Jiwani, Sai Babu Patarlapalli, Fenyong Yao, Fugui Zhu, Chelsea Barrows, Arzoo Patel, , Joseph G. Gleeson

The paper uses genomic mosaicism to study clonal dynamics of trunk neural crest-derived ganglia, finding conserved developmental patterns across species.

Nature · Apr 1, 2026Peer-reviewedDevelopmental Biology

A phenotypic brain organoid atlas for neurodevelopmental disorders

Lu Wang, Yuji Nakamura, Junhao Li, David Sievert, Yang Liu, Toan D. Nguyen, Prudhvi Sai Jetti, Ethan Thai, Rachel Yibei Zhou, Jiaming Weng, Naomi Meave Ojeda, Manya Yadavilli, Robyn Ann Howarth, Kevin Camey, Niyati Banka, , Joseph G. Gleeson

The paper presents a brain organoid atlas of 352 patient-derived iPSCs from neurodevelopmental disorders, showing disease-specific cellular defects in organoids.

bioRxiv · Sep 12, 2025 · PreprintNeuroscience

Microhomology-Mediated Circular DNA Formation from Oligonucleosomal Fragments During Spermatogenesis

Jun Hu, Zhe Zhang, Sai Jin Xiao, Yalei Cao, Yinghong Chen, Jiaming Weng, Hui Jiang, Wei Li, Jiayu Chen, Chao Liu

The paper identifies widespread extrachromosomal circular DNA (eccDNA) formation during spermatogenesis and shows microhomology-mediated end joining is the major biogenesis mechanism.

eLife · May 5, 2023Peer-reviewedGenomics