scRNA-seq revealed the rules for CDR3 length pairing in TCR beta and alpha chains and BCR heavy and light chains in human and mice
Jiaping Xiao, Jun Li, Yingjie Wu, Lanwei Zhu, Qi Peng, Yuanyuan Xu, Xinsheng Yao
This study uses scRNA-seq to analyze CDR3 length pairing rules in TCR and BCR chains across human and mouse cells, revealing species-specific differences and increased plasticity in humans.
Genomics · Apr 7, 2026Peer-reviewedImmunology