Author

Jiawei Chang

UNSW Sydney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Elham Hosseini BeheshtiiD· 1 shared Fei Tian· 1 shared Heloisa Helena MilioliiD· 1 shared Hong-Mei ZhangiD· 1 shared Hongchen JiiD· 1 shared Jianwei Wu· 1 shared Mekonnen Sisay Shiferaw· 1 shared Mengdi Zheng· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Elham Hosseini BeheshtiORCID

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2 papers

Recent·Most cited

Structural semantic evolutionary distance (SSED) unifies the selection of cancer driver genes across macroevolution and tumorigenesis.

Hongchen Ji, Q Y Zhang, Jianwei Wu, Fei Tian, Xiangxu Wang, Xiao Chai, Jiawei Chang, Mengdi Zheng, X. M. Li, Hong-Mei Zhang

This paper introduces SSED, a metric using ESM-3 to quantify evolutionary divergence, showing cancer driver genes are structurally constrained and that oncogenic mutations follow similar principles, predicting immune response.

bioRxiv · Dec 19, 2025 · PreprintGenetics

Silencing the signal: The metastasis suppressor NDRG1 disrupts exosome-mediated crosstalk in pancreatic cancer

Jiawei Chang, Shafi Alenizi, Heloisa Helena Milioli, Winston Lay, Saranya Pounraj, Yujie Li, Mekonnen Sisay Shiferaw, Elham Hosseini Beheshti, Žaklina Kovačević

This paper shows that NDRG1 suppresses pancreatic cancer metastasis by disrupting exosome-mediated communication between cancer cells and the tumor microenvironment.

bioRxiv · Oct 15, 2025 · PreprintCancer Biology