Author

Jie Fang

Beijing University of Chinese Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Molecular Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:Hi-C· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alfredo Jose Florez ArizaiD· 1 shared Benjamin KaeseriD· 1 shared Dong LiuiD· 1 shared Eva NogalesiD· 1 shared Fanhui JiniD· 1 shared Jieming QuiD· 1 shared Jingjing LiiD· 1 shared Lijun FuiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMolecular Biology

Alfredo Jose Florez ArizaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Integrative Multi-cohort Transcriptomics and Network Pharmacology Analysis Reveals Key Network Nodes and Potential Drug Clues in PCOS Granulosa Cells

Xuan Zhang, Jie Fang, Zhinan Liu, S.-J. Li, Fanhui Jin, Linlin Guo, Ruonan Qiang, Yinan Zhu, Tingting Hou, Jingjing Li, Yanfeng Liu

The paper identifies key genes and potential drugs for PCOS by integrating transcriptomics and network pharmacology across multiple cohorts.

bioRxiv · Apr 6, 2026 · PreprintSystems Biology

Structural insights into transcriptional regulation by the helicase RECQL5

Alfredo Jose Florez Ariza, Nicholas Z. Lue, Patricia Grob, Benjamin Kaeser, Jie Fang, Susanne A. Kassube, Eva Nogales

This study determines the structure of RECQL5-bound Pol II elongation complexes using cryo-EM, revealing how RECQL5 stabilizes Pol II and modulates its translocation state to reduce transcription stress.

Nature Structural & Molecular Biology · Jul 7, 2025Peer-reviewedMolecular Biology

Progesterone is an Inducement of Heritable Pulmonary Arterial Hypertension with BMPR2 Mutation

Weiping Hu, Si-Jin Zhang, Yongjie Ding, Jie Fang, Ling Zhou, Simin Xie, Xiao Ge, Lijun Fu, Qing Yun Li, Jieming Qu, Shanqun Li, Dong Liu

The paper investigates how progesterone induces heritable pulmonary arterial hypertension in BMPR2 mutation carriers, showing it promotes PASMC proliferation via ERK pathway activation.

bioRxiv · Apr 21, 2023 · PreprintMolecular Biology