Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimers disease
Jie Yeap, Chaitra Sathyaprakash, Jamie Toombs, Jane Tulloch, Cristina Scutariu, Jamie L. Rose, Karen Burr, Caitlin Davies, Martí Colom‐Cadena, Siddharthan Chandran, Charles H. Large, Matthew JM Rowan, Martin J. Gunthorpe, Tara L. Spires‐Jones
This study shows reducing Kv3.4 levels in a mouse model of Alzheimer's disease reduces synapse loss and changes in spine morphology.
Brain and Neuroscience Advances · Jan 1, 2022Peer-reviewedNeuroscience