Drosophila melanogaster model of RVCL-S demonstrates age dependent disease progression
Elena Gracheva, Abigail Matt, Fei Wang, Raymond Hsin, Hongwu Liang, Xiangping Ouyang, Jimin Ding, Jonathan J. Miner, Chao Zhou
This study establishes a Drosophila model of RVCL-S that recapitulates disease features, showing vascular deterioration and reduced lifespan in TREX1 mutant flies.
bioRxiv · Nov 10, 2025 · PreprintGenetics