ChAI-Net learns a regulatory code for chromatin co-accessibility
Jodi Lee, Kaite Zhang, Ethan Shurberg, Vijay S. Ramani, Katherine S. Pollard
The paper introduces ChAI-Net, a deep learning model that predicts chromatin co-accessibility from DNA sequences in mouse embryonic stem cells, revealing sequence motifs that govern coordinated TF binding.
bioRxiv · Oct 31, 2026 · PreprintGenomics