Chaotic propagation of spatial cytoskeletal instability modulates integrity of podocyte foot processes
Cibele V Falkenberg, Evren U Azeloglu, Mark Stothers, Thomas J Deerinck, Yibang Chen, John C He, Mark H. Ellisman, James C. Hone, Ravi Iyengar, Leslie M. Loew
The paper uses 3-D microscopy and dynamical models to show that spatially-specific actin cytoskeleton regulation in podocytes leads to chaotic foot process instability and glomerular pathophysiology.
bioRxiv · Jul 26, 2016Biophysics