Author

John Guatelli

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Charlotte A. StonehamiD· 3 shared Peter W. RamireziD· 2 shared Aaron O. AngersteiniD· 1 shared Amalia De Leon· 1 shared Amalia De-leon· 1 shared Angus FuoriiD· 1 shared Francisco M. AcostaiD· 1 shared Hannah S. SperberiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Charlotte A. StonehamORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Cluster of Acidic Residues in the Cytoplasmic Domain of SARS-CoV-2 Spike is Required for Virion-Incorporation and Infectivity

Charlotte A. Stoneham, Rajendra Singh, Amalia De Leon, Petra Tafelmeyer, Francisco M. Acosta, Angus Fuori, Michael Anderson, Peter W. Ramirez, Hannah S. Sperber, Satish K. Pillai, Mary K. Lewinski, John Guatelli

This study identifies an acidic cluster motif in the SARS-CoV-2 Spike protein's cytoplasmic domain essential for virion incorporation and infectivity.

PLoS ONE · Mar 12, 2026Peer-reviewedMolecular Biology

HIV-1 Nef uses a conserved pocket to recruit the N-terminal cytoplasmic tail of Serinc3

Mohammad Karimian Shamsabadi, Charlotte A. Stoneham, Amalia De-leon, Tony Fares, John Guatelli, Xiaofei Jia

This study identifies how HIV-1 Nef recruits Serinc3 by binding its N-terminal tail, revealing a conserved pocket important for antiviral resistance and drug target discovery.

Viruses · Dec 19, 2025Peer-reviewedBiochemistry

Sensitivity to Monoclonal Antibody 447-52D and an Open Env Trimer Conformation Correlate Poorly with Inhibition of HIV-1 Infectivity by SERINC5

Aaron O. Angerstein, Charlotte A. Stoneham, Peter W. Ramirez, John Guatelli, Thomas Vollbrecht

The paper tests if the open Env trimer conformation, as indicated by sensitivity to 447-52D, correlates with sensitivity to SERINC5 inhibition of HIV-1 infectivity, finding no strong correlation.

Virology · Jun 17, 2020Peer-reviewedMolecular Biology