Author

Jonatan Leffler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Christian Pasquali· 2 shared Alexander N. Larcombe· 1 shared Anthony Bosco· 1 shared Anya Jones· 1 shared Deborah H. StricklandiD· 1 shared Deborah Strickland· 1 shared Jean-Francois Lauzon-Joset· 1 shared Jeff Lauzon-Joset· 1 shared

Activity by Year

2017-2017 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Christian Pasquali

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2 papers

Recent·Most cited

Transplacental protection against asthma by maternal treatment with a bacterial-derived immunomodulatory agent

Kyle T. Mincham, Naomi M. Scott, Jean-Francois Lauzon-Joset, Jonatan Leffler, Alexander N. Larcombe, Philip A. Stumbles, Sarah A. Robertson, Christian Pasquali, Patrick G. Holt, Deborah H. Strickland

The paper shows maternal treatment with OM85 reduces offspring asthma susceptibility in mice by targeting dendritic cell precursors.

bioRxiv · Dec 11, 2017 · PreprintImmunology

Protection against maternal infection-associated fetal growth restriction - proof-of-concept with a microbial-derived immunomodulator OM85: safety and efficacy data

Naomi Scott, Jeff Lauzon-Joset, Anya Jones, Kyle Mincham, Niamh Troy, Jonatan Leffler, Michael Serralha, Susan Prescott, Sarah Robertson, Christian Pasquali, Anthony Bosco, Patrick Holt, Deborah Strickland

This study shows that OM85, an immunomodulator, reduces fetal loss and growth restriction in pregnant mice exposed to bacterial LPS or influenza, by modulating maternal inflammatory responses without impairing anti-microbial defenses.

Mucosal Immunology · May 1, 2017Peer-reviewedImmunology