Pulmonary Vascular Endothelial Dysfunction is Induced by Non-Pulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model
Jonathan Hyde, Michael A. Smith, Naveen Swami, John H. Hwang, Yenchun Chao, Jason B. Boehme, Gary W. Raff, Casper Noah Nilsson, Wenhui Gong, Gail H. Deutsch, Eric G. Johnson, Ting Wang, Stephen M. Black, Sanjeev A. Datar, Emin Maltepe, Jeffrey R. Fineman
This study shows that non-pulsatile pulmonary blood flow after a Glenn procedure causes endothelial dysfunction in lambs, independent of hypoxemia and polycythemia.
Comprehensive physiology · Nov 10, 2025Peer-reviewedPhysiology