Author

Jonathon D. Klein

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Shondra M. Pruett‐MilleriD· 2 shared Alanna V. Van HuizeniD· 1 shared Antonio Morales‐HernándeziD· 1 shared Beisi XuiD· 1 shared Brett J.W. TeubneriD· 1 shared Byoung-Kyu ChoiD· 1 shared Camenzind G. RobinsoniD· 1 shared Chablis D. Shreffler· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Shondra M. Pruett‐MillerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LRRC57/RABIN is a presynaptic inhibitor of Rab GTPases in glutamatergic neurons

Dušan Garić, Jonathan G. Murphy, Brett J.W. Teubner, Christopher M. Davenport, Chablis D. Shreffler, Laura J. Janke, Woo Jung Cho, Zhiping Wu, Meghan G. McReynolds, Sarayut Phasuk, Jason Y. Fu, De'Keerah A. Lewis, Thomas Confer, Jonathon D. Klein, Melissa Johnson, , Stanislav S. Zakharenko

The paper identifies LRRC57/RABIN as a presynaptic inhibitor of Rab GTPases in glutamatergic neurons, showing it regulates neurotransmitter release and prevents epileptiform activity.

bioRxiv · Sep 28, 2026 · PreprintNeuroscience

Elevated endocytic trafficking mediated by GPRASP2 maintains HSC fidelity.

Alanna V. Van Huizen, Mattieu Zhai, Haruhito Totani, Dewmi Sandaru Rathnayake, Emilia Kooienga, Ishani Sharma, Zakiya Kelley, Madeleine Rodgers, Federica Zanotti, lance Palmer, Kate Tisdale, Preeti Dabas, Jessica Nunes, Dirk Loeffler, Shondra Pruet-Miller, , Shannon McKinney‐Freeman

The paper shows that elevated endocytic trafficking via GPRASP2 maintains HSC quiescence and prevents functional exhaustion.

bioRxiv · Feb 11, 2026 · PreprintCell Biology

Deciphering acquired resistance mechanisms to sustained auxin-inducible protein degradation in cells and mice

Judith W. Hyle, Zhenling Liu, Shaela Fields, Jifeng Yang, Xinyan Chen, Wenjie Qi, Qiong Zhang, Byoung-Kyu Cho, Young Ah Goo, Xiuling Li, Jack E. Sublett, Qianqian Li, Liusheng He, Jonathon D. Klein, Peng Xu, , Chunliang Li

This study identifies four resistance mechanisms to sustained auxin-inducible protein degradation in human cells and mice using the AID2 system.

bioRxiv · Sep 21, 2025 · PreprintCell Biology