Author

Jordan Brown

Calico Life Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetic & Genomic Medicine· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

David G. HendricksoniD· 3 shared Anil RajiD· 2 shared Daphna RothschildiD· 2 shared Jonathan K. PritchardiD· 2 shared Manuel HotziD· 2 shared Maria BarnaiD· 2 shared Nicole L. Fong· 2 shared Aaron W. StebbinsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

David G. HendricksonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

PTPN1/2 inhibits alveolar macrophage-mediated control of lung metastasis

Yue Liu, Im-Meng Sun, Marc Creixell, Jordan Brown, Samir Kharbanda, James J. Lee, Varahram Shahryari, Kayley Hake, Jacqueline O'Hara, Kenneth J. Finn, Nianxin Yang, Lolita Penland, Jiaxi Wang, Ka Man Li, John Balibalos, , Jonathan D. Powell

This study shows that inhibiting PTPN1/2 enhances alveolar macrophage anti-metastatic activity through IFN-gamma-STAT1 signaling, offering a therapeutic strategy for metastasis.

bioRxiv · Feb 26, 2026 · PreprintImmunology

Ribosomal DNA copy number variation shapes human physiology and disease risk

Anil Raj, Jordan Brown, Nathaniel H. Thayer, Manuel Hotz, Irene Lam, Nicole L. Fong, Elena P. Sorokin, Marjola Thanaj, Daphna Rothschild, Jonathan K. Pritchard, Maria Barna, David G. Hendrickson

The paper analyzes rDNA copy number variation in humans, finding distinct associations with metabolic diseases and growth traits.

medRxiv · Jan 13, 2026 · PreprintGenetic & Genomic Medicine

Ribosome heterogeneity arising from common and rare rRNA sequence variants affects diverse human phenotypes

Daphna Rothschild, Anil Raj, Jordan Brown, Nathaniel Thayer, Manuel Hotz, David G. Hendrickson, Jonathan K. Pritchard, Maria Barna

The paper identifies rRNA sequence variants affecting human traits and diseases by analyzing UK Biobank data and developing the RiboVAn method.

medRxiv · Sep 2, 2025 · PreprintGenetic & Genomic Medicine