Author

Im-Meng Sun

Calico Life SciencesORCID 0009-0000-4358-5473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Chirag H. PateliD· 2 shared Jonathan D. PowelliD· 2 shared Aaron W. StebbinsiD· 1 shared Ada J. Tam· 1 shared Barbara S. Slusher· 1 shared David G. HendricksoniD· 1 shared Evangelia MalahiasiD· 1 shared Fiona Elizabeth McAllisteriD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Chirag H. PatelORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 26, 2026

PTPN1/2 inhibits alveolar macrophage-mediated control of lung metastasis

Yue Liu, Im-Meng Sun, Marc Creixell…·Jonathan D. Powell

This study shows that inhibiting PTPN1/2 enhances alveolar macrophage anti-metastatic activity through IFN-gamma-STAT1 signaling, offering a therapeutic strategy for metastasis.

DOI 10.64898/2026.02.25.707995

mousespatial transcriptomics

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 3, 2019

Targeting glutamine metabolism enhances tumor specific immunity by inhibiting the generation of MDSCs and reprogramming tumor associated macrophages

Min-Hee Oh, Im-Hong Sun, Liang Zhao…·Jonathan D. Powell

This study shows that targeting glutamine metabolism in tumors reduces MDSC generation, increases inflammatory macrophages, and enhances anti-tumor immunity, making checkpoint-resistant tumors responsive to immunotherapy.

DOI 10.1101/656553

mouseexperimental assay

𝕏 PostBluesky