Restoration of Keratinocyte Homeostasis Drives Resolution of Skin Inflammation
Dennis Gruszka, Rachael Wasikowski, Roopesh Singh Gangwar, Brian Richardson, Josh Webster, Jennifer P. Fox, Michele M. Mumaw, Athira Sivadas, Mark J. Cameron, Thomas S. McCormick, Lam Cheung Tsoi, Johann Eli Gudjonsson, Nicole L. Ward
The paper shows that restoring keratinocyte homeostasis reduces skin inflammation by reversing gene programs and normalizing epidermal architecture in a murine model.
bioRxiv · Mar 4, 2026 · PreprintCell Biology