Author

Joshua David

University of Calgary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Ayshin MehrabiiD· 1 shared Cole Chute· 1 shared Costin N. AntonescuiD· 1 shared Gerald PfefferiD· 1 shared Jingti Deng· 1 shared Luke WisemaniD· 1 shared Mashiat ZamaniD· 1 shared Pina ColarussoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Ayshin MehrabiORCID

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1 paper

Recent·Most cited

Pathogenic Mitofusin 2 variants causing myopathy drive endosomal mtDNA release and inflammation

Mashiat Zaman, Joshua David, Ayshin Mehrabi, Cole Chute, Jingti Deng, Tyler Soule, Luke Wiseman, Costin N. Antonescu, Pina Colarusso, Gerald Pfeffer, Timothy E. Shutt

The paper identifies how pathogenic MFN2 variants cause mtDNA release into endosomes and mitochondrial-derived vesicles, triggering inflammation and myopathy, and suggests a therapeutic strategy using integrated stress response activation.

medRxiv · Sep 29, 2026 · PreprintGenetic & Genomic Medicine