Author

Julia Greissl

Microsoft (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Assay:CITE-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Harus Jabran ZahidiD· 4 shared Harlan S. RobinsiD· 3 shared Damon MayiD· 2 shared Haiyin Chen‐HarrisiD· 2 shared Marco Garcia Noceda· 2 shared André FrankeiD· 1 shared Bernd BokemeyeriD· 1 shared Bryan Howie· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Harus Jabran ZahidORCID

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Author profile →

4 papers

Recent·Most cited

HLA Alleles Imprint Distinct Biases in the Usage Preferences of TCR Vβ segments

Leonardo V. Castorina, Matthew T. Noakes, Lorenzo Pisani, Julia Greissl, Harlan Robins, Haiyin Chen‐Harris, Harus Jabran Zahid

This study identifies HLA allele-specific biases in TCR Vβ usage, showing germline-encoded preferences shape TCR-HLA compatibility and influence TCR-pHLA specificity.

bioRxiv · Mar 19, 2026 · PreprintImmunology

A Fundamental Relationship between TCR Diversity, Repertoire Size and Systemic Clonal Expansion: Insights from 30,000 TCRβ Repertoires

Harus Jabran Zahid, Damon May, Harlan S. Robins, Julia Greissl

The paper analyzes TCRβ repertoires from 30,000 individuals to show that TCR diversity is primarily determined by repertoire size and the frequency of the 1,000 most abundant clones, explaining 96% of variance in diversity.

Frontiers in Immunology · Jan 8, 2026Peer-reviewedImmunology

Antigen-driven expansion of public clonal T cell populations in inflammatory bowel diseases

Mitchell W. Pesesky, Ramit Bharanikumar, Lionel Le Bourhis, Hesham ElAbd, Elisa Rosati, Cara L. Carty, Namita Singh, Bernd Bokemeyer, Stefan Schreiber, Siegfried Görg, Marco Garcia Noceda, Paidamoyo Chapfuwa, Rachel M. Gittelman, Damon May, Jennifer N. Dines, , Matthieu Allez

The paper identifies public TCRB sequences expanded in CD or UC, associated with HLA alleles and antigen-specific immune responses, showing differential expansion in CD compared to UC and healthy controls.

Journal of Crohn s and Colitis · Mar 13, 2025Peer-reviewedImmunology

The Immune-Mutation Axis of Cancer Incidence: Insights from 30,000 TCRβ Repertoires

Harus Jabran Zahid, Matthew E. Lee, Ruth T. Taniguchi, Gheath Alatrash, Thomas McFall, Marco Garcia Noceda, Harlan S. Robins, Julia Greissl

The paper analyzes TCRβ repertoires from 30,000 individuals to show that immune decline with age correlates with cancer incidence, revealing an immune-mutation balance in carcinogenesis.

bioRxiv · Oct 21, 2024 · PreprintCancer Biology