Image-Based Profiling of Induced Trophoblast Stem Cells Identifies Signatures Associated with Sex, Schizophrenia Genomic Risk and Placental Stress
Frank J. Piscotta, Jiyoung Kim, Jisu Ha, Bonna J. Sheehan, Julia Johnston, J PETERS, T. B. Hyde, Brady J. Maher, Juan C. Caicedo, Daniel R. Weinberger, Evgeny Shlevkov, Gianluca Ursini
The paper uses image-based profiling of hiPSC-derived trophoblasts to identify SCZ risk signatures linked to sex, placental genomic risk, and hypoxic stress.
bioRxiv · Jan 7, 2026 · PreprintNeuroscience