NeurosciencebioRxivPreprint
Screening of a kinase inhibitor library in human Huntington disease iPSC derived striatal precursor neurons reveals a neuroprotective effect of PKC alpha and PKC beta1 inhibition
Mali Jiang, Tianze Shi, Ritika Miryala…·Christopher A. Ross
The paper screens a kinase inhibitor library in HD iPSC-derived neurons to identify PKC alpha and beta1 inhibition as neuroprotective against mutant huntingtin toxicity.
DOI 10.1101/2025.09.18.677178