De Novo Design of Anti-Aging Peptides
Yan Pan, Fan Li, Nan Zhang, Jiexin Zheng, Zhong Jin, Hongxia Cai, Hongbao Ma, Wenjing Zhang, Jingyuan Zhu, Wentao Xu, Yiwen Gong, Ruofei Li, Rui Liang, Guojun Li, Haiming Jing, , Bo Xian
This paper introduces ElixirSeeker2, a computational framework for de novo design of anti-aging peptides, which identifies novel candidates effective in delaying cellular senescence and improving locomotor activity in aged C. elegans.
bioRxiv · Oct 4, 2025 · PreprintBioinformatics