Murine Progeria Model Exhibits Delayed Fracture Healing with Dysregulated Local Immune Response
Victoria R. Duke, Marc J. Philippon, Dane R.G. Lind, Herbert G. Kasler, Kohei Yamaura, Matt Huard, Molly E. Czachor, Justin F.M. Hollenbeck, Justin Brown, Alex Garcia, Naomasa Fukase, Ralph Marcucio, Anna Laura Nelson, William S. Hambright, Dustin M. Snapper, , Chelsea S. Bahney
This study shows that Zmpste24-/- mice have delayed fracture healing with immune dysregulation and increased cellular senescence compared to wild-type mice.
bioRxiv · May 29, 2024 · PreprintMolecular Biology