Pyroptosis-dependent and -independent cross-priming of CD8+ T cells by intestinal epithelial cell-derived antigen
K. A. Deets, R. D. Nichols, I. Rauch, R. E. Vance
The paper shows that IEC-derived antigens can cross-prime CD8+ T cells through both pyroptosis-dependent and -independent pathways involving cDC1.
bioRxiv · Jul 8, 2021Immunology