Author

K. Alvarez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Canard· 2 shared F. Ferron· 2 shared M. Feracci· 2 shared A. Chazot· 1 shared A. Moussa· 1 shared C. T. De Jesus· 1 shared C. Zimberger· 1 shared E. Decroly· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

B. Canard

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2 papers

Recent·Most cited

The activation chain of the broad-spectrum antiviral bemnifosbuvir at atomic resolution

A. Chazot, C. Zimberger, M. Feracci, A. Moussa, S. Good, J.-P. Sommadossi, K. ALVAREZ, F. Ferron, B. Canard

This paper reveals the activation pathway of bemnifosbuvir to its active form AT-9010, showing the required enzymes and structural insights into the process.

bioRxiv · Feb 16, 2024 · PreprintBiochemistry

A high-throughput fluorescence polarization assay to discover inhibitors of arenavirus and coronavirus exoribonucleases

S. G. Hernandez Tapia, M. Feracci, C. T. De Jesus, P. El-Kazzi, R. Kaci, L. Garlatti, E. Decroly, B. Canard, F. Ferron, K. Alvarez

This paper develops a high-throughput fluorescence polarization assay to screen inhibitors of exoribonucleases from arenaviruses and coronaviruses and validates it with a small compound library.

bioRxiv · Apr 2, 2021 · PreprintBiochemistry