Flexible pivoting of the pleckstrin homology domain in dynamin catalyzes fission: Insights into the molecular degrees of freedom
K. Baratam, K. Jha, A. Srivastava
This study uses multiscale simulations to show that the PHD domain of dynamin1 modulates membrane flexibility and orientation to facilitate rapid fission during synaptic vesicle recycling.
bioRxiv · Dec 20, 2020 · PreprintBiophysics