Targeting plasma membrane and mitochondrial instability in breast cancer cells and breast epithelial to mesenchymal transition-model cells by adamantyl diaza-crown ether ZG613
K. Ester, M. Mioc, P. Spurny, D. Bonhenry, M. Marjanovic, L. Uzelac, J. Gabrilo, T. Sumanovac, W. Schreibmayer, K. Majerski, B. Minofar, J. Ludwig, M. Kralj
This study evaluates ZG613's ability to disrupt plasma membranes and mitochondria in breast cancer and EMT-model cells, showing reduced tumor growth in vivo.
bioRxiv · Sep 30, 2022 · PreprintCancer Biology