Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia
B. P. Bergeron, K. R. Barnett, K. R. Bhattarai, R. J. Mobley, B. S. Hansen, A. Brown, K. Kodali, A. A. High, S. Jeha, C.-H. Pui, J. Peng, S. M. Pruett-Miller, D. Savic
The paper identifies mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia, linking TLE1 cis-regulatory disruptions to GC resistance.
bioRxiv · Jan 20, 2023Cancer Biology